One versatile instrument to power innovation
- Learn how the NX One can streamline your workflows, accelerate your research, and open up new opportunities for discovery.
- Explore our Application Notes & mammalian and non-mammalian library which highlight examples of the Nodexus NX One instrument, consumables, and software.
- The NX One simplifies the complexities of single-cell sorting and dispensing at a price anyone can afford.
Cell line & antibody development
Clonal expansion has never been simpler. Use the NX One’s flexible sorting modes to easily isolate the high-producing recombinant cell lines.
Expression-Based Cell Line Development
The cell line development process is essential for biomedical and basic research as it broadly contributes to the efficiency, quality, and consistency of experimental outcomes, e.g., newer therapeutic approaches such as gene therapy require the development of monoclonal cell lines to test the efficacy and toxicity of viral vector transduction…
CRISPR & gene editing
Optimize your gene editing efficiency by detecting and isolating transfected cell populations using the NX One’s highly-specific 1- to 3-color detection.
Gentle, Efficient, and Reproducible Single Cell Sorting of Human iPSCs
Human induced pluripotent stem cells (iPSCs) hold immense significance and potential in regenerative medicine and disease modeling. These cells, derived from adult somatic cells like the skin or blood cells, can be reprogrammed to revert to a pluripotent state, which enables them to differentiate into any cell type in the human body (Mahajani et al., 2019)…
Highly Efficient, Gentle, and Contamination-Free Single Cell Sorting
Single-cell sorting is a critical technique in biological and medical research, enabling scientists to isolate and study specific cell populations precisely [1]. While traditional cell sorting methods have been effective, there is an increasing recognition of the importance of sorting one cell per well using a gentle sorting system when sorting single cells…
Cell & gene therapy
Protect the sterility and minimize cross-contamination of your precious samples using the NX One’s individually-packed, disposable cartridges.
Optimizing Single Cell Sorting: Input Concentrations and Ratios
The central objective of single-cell sorting is to isolate specific cell types from larger populations to elucidate their function, which is essential for understanding the role they play in disease development and for deriving potential therapeutic approaches…
Single-cell genomics & RNA-Seq
Isolate single cells with minimal perturbation to biology for your downstream analysis and ‘omics needs.
Nodexus – University of Chicago Poster
Gentle stem cell isolation
Preserve the viability of fragile cell populations that typically suffer through conventional sorting methods by leveraging the NX One’s gentle operating pressures (less than 1 psi) for sorting and dispensing.
Gentle, Efficient, and Reproducible Single Cell Sorting of Human iPSCs
Human induced pluripotent stem cells (iPSCs) hold immense significance and potential in regenerative medicine and disease modeling. These cells, derived from adult somatic cells like the skin or blood cells, can be reprogrammed to revert to a pluripotent state, which enables them to differentiate into any cell type in the human body (Mahajani et al., 2019)…
Neuronal Patterning of NX One Sorted Pluripotent Monoclonal iPSCs
Human Induced Pluripotent Stem Cells (hiPSCs) are immensely valuable in research and drug discovery. These cells offer a unique platform to study disease mechanisms, model patient-specific conditions, screen potential drug candidates, and test the efficiency of gene editing strategies like CRISPR. Obtaining monoclonal iPSC lines thus becomes crucial…
Yeast, nuclei, algae, organoids & more
Accurately sort and characterize a range of particle types as small as yeast and as large as nascent organoids and cell clusters – the NX One’s disposable, contamination-free cartridge supports 2 – 60 µm particles with ease.
New Application Note!
Yeast display is an effective method for screening protein binding affinity.
Generating yeast clones through conventional methods such as colony picking and serial dilutions are low throughout, highly labor intensive, and nonspecific…
Plug-and-Play Sorting for Large Particles: 60μm and Beyond
Size-based particle analysis and sorting are crucial in biological applications as the function, origin, or type of biological particles can be traced using cell size as a metric. For traditional fluorescence-activated cell sorting systems, processing large (>30 μm diameter) particles or heterogeneous…
Sample Library
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Mammalian Cells
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Non-Mammalian Cells
| CACO-2 |
| T-Cells |
| Chinese Hamster Ovary (CHO) |
| HCC1569 |
| HEK293 |
| HeLa |
| iHEP & other Hepatocytes |
| iPSC (wild type and Parkinson’s-derived) |
| Jurkat |
| K562 |
| L929 |
| MCF7 |
| MDA-MB-231 |
| Primary Human Skeletal Muscle Cells |
| HT1080 |
| U87 |
| PBMCs |
| Nascent Organoids | Gibco Viral Production Cells (VPCs) |
| Keratinocytes | PaCa |
| U-2 OS |
| Yeast |
| Nannochloropsis Algae |
| Bacteria (E. coli) |
| Protoplasts |
| Hydrogels (60-75 micron) |
| Oil-in-water emulsion droplets (75+ micron) |
| Mitochondria |
| Partillion Nanovials |
